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＜p＞Since the publication of the best-selling first edition, much has been discovered about Saccharomyces cerevisiae, the single-celled fungus commonly known as baker's yeast or brewer's yeast that is the basis for much of our understanding of the molecular and cellular biology of eukaryotes. This wealth of new research data demands our attention and r＜/p＞画面が切り替わりますので、しばらくお待ち下さい。
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＜p＞Since their discovery approximately 25 years ago, adenosine receptors have now emerged as important novel molecular targets in disease and drug discovery. These proteins play important roles in the entire spectrum of disease from inflammation to immune suppression. Because of their expression on a number of different cell types and in a number of different organ systems they play important roles in specific diseases, including asthma, rheumatoid arthritis, Parkinson’s disease, multiple sclerosis, Alzheimer’s disease, heart disease, stroke, cancer, sepsis, and obesity. As a result of intense investigations into understanding the molecular structures and pharmacology of these proteins, new molecules have been synthesized that have high specificity for these proteins and are now entering clinical trials. These molecules will define the next new classes of drugs for a number of diseases with unmet medical needs.＜/p＞画面が切り替わりますので、しばらくお待ち下さい。
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＜p＞This volume focuses on the classical theory of number-theoretic functions emphasizing algebraic and multiplicative techniques. It contains many structure theorems basic to the study of arithmetic functions, including several previously unpublished proofs. The author is head of the Dept. of Mathemati＜/p＞画面が切り替わりますので、しばらくお待ち下さい。
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＜p＞This work provides a basic understanding of the physical background and engineering considerations required for the design of IR systems, examining all components and combining them into examples of current surveillance systems. This second edition presents: new coverage of state-of-the-art optical systems, including lightweight mirrors and adaptiv＜/p＞画面が切り替わりますので、しばらくお待ち下さい。
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＜p＞Offering expert, comprehensive guidance on the basic science, diagnosis, and treatment of acute musculoskeletal injuries and post-traumatic reconstructive problems, Skeletal Trauma, 6th Edition, brings you fully up to date with current approaches in this challenging specialty. This revised edition is designed to meet the needs of orthopaedic surgeons, residents, fellows, and traumatologists, as well as emergency physicians who treat patients with musculoskeletal trauma. International thought leaders incorporate the latest peer-reviewed literature, technological advances, and practical advice with the goal of optimizing patient outcomes for the full range of traumatic musculoskeletal injuries. - Offers complete coverage of relevant anatomy and biomechanics, mechanisms of injury, diagnostic approaches, treatment options, and associated complications. - Includes eight new chapters dedicated to advances in technology and addressing key problems and procedures, such as Initial Evaluation of the Spine in Trauma Patients, Management of Perioperative Pain Associated with Trauma and Surgery, Chronic Pain Management (fully addressing the opioid epidemic), Understanding and Treating Chronic Osteomyelitis, and more. - Features a complimentary one-year subscription to OrthoEvidence, a global online platform that provides high-quality, peer-reviewed and timely orthopaedic evidence-based summaries of the latest and most relevant literature. Contains unique, critical information on mass casualty incidents and war injuries, with contributions from active duty military surgeons and physicians in collaboration with civilian authors to address injuries caused by road traffic, armed conflict, civil wars, and insurgencies throughout the world. - Features important call out boxes summarizing key points, pearls and pitfalls, and outcomes. - Provides access to nearly 130 instructional videos that demonstrate principles of care and outline detailed surgical procedures. - Contains a wealth of high-quality illustrations, full-color photographs, and diagnostic images. - Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.＜/p＞画面が切り替わりますので、しばらくお待ち下さい。
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＜p＞Uma ferramenta indispens?vel ao estudo da Cirurgia Vascular, Cirurgia Endovascular e Angiologia. Estamos chegando na Quarta Edi??o da obra Cirurgia Vascular. ? de se esperar que uma nova edi??o seja pensada, esmiu?ada e encarada sempre como alguma coisa que se pretende melhor que a edi??o anterior.Ofoco ? o ensino e a melhor maneira de torn?-lo mais eficiente e proveitoso. A forma na qual este livro ? estruturado visa a proporcionar uma leitura agrad?vel, sem tornar penoso o processo de absor??o do conhecimento. Comamudan?a c?lere por que passa o mundo em todos os seus aspectos, ? imperativo uma adapta??o para novas propostas did?ticas. Esta nova proposta did?tica vemda vontade dos editores de procuraremmanter-se alinhados aos novos tempos que correm. Olivro n?o est? organizado por patologia,mas por blocos anat?micos. Emcada bloco, o leitor poder? encontrar tudo o que se refere a esta fra??o anat?mica, ou seja, anatomia, vias de acesso, exames de imagem e outros, al?m de todas as patologias vasculares que afetemeste segmento. Existemcap?tulos que n?o podem ser enquadrados em blocos anat?micos, ou se referem a todos, e estes ficar?o nas rubricas de Cap?tulos B?sicos. Em nossa ?tica, o livro-texto continua a representar um utens?lio indispens?vel ao estudo, desde que ele ? alicerce, o conhecimento j? sedimentado, a partir do qual o leito vai acrescentando o novo, deumaformaorganizada. Os autores＜/p＞画面が切り替わりますので、しばらくお待ち下さい。
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＜p＞Cellular and Molecular Biology of the Renin-Angiotensin System provides the first review and update of the state-of-the-art cellular and molecular aspects of the renin-angiotensin system. The book presents detailed analyses from world experts on each component of this system, including future directions. Topics range from angiotensin II receptor subtypes to processing of renin to the use of transgenic animal models for studying the role of this system in hypertension. Cellular and Molecular Biology of the Renin-Angiotensin System is essential reading for physiologists of the renin-angiotensin system, endocrinologists, cardiovascular specialists, renal physiologists, and neurobiologists.＜/p＞画面が切り替わりますので、しばらくお待ち下さい。
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＜p＞The most misunderstood and complex subject in medicine is the hyperpathic pain of sympathetic dystrophy. More common than previously thought, it comprises between 10 and 20 percent of chronic pain patients. Understanding this self-perpetuating pain -- which ""never stops"" -- requires unbiased knowledge of physiology and pathology.＜br /＞ Chronic Pain: Reflex Sympathetic Dystrophy, Prevention, and Management is devoted to the subject of Reflex Sympathetic Dystrophy (RSD). The book classifies the different stages of RSD and describes the qualitative and quantitative differences between natural endorphins and synthetic narcotics. Included are long-term follow-ups on sympathectomy patients.＜br /＞ This important reference explains why sympathectomy fails, but nerve block and physiotherapy is successful in the treatment of RSD. In addition, the mechanism of development of RSD is clarified through an extensive collection of drawings and anatomical pictures as well. Other topics include thermographic methods for the diagnosis of RSD, the role of ACTH in the management of chronic pain, and comparisons between the effects of ACTH and those of corticosteroids.＜/p＞ ＜p＞Features＜/p＞ ＜p＞Classifies the different stages of RSD＜/p＞ ＜p＞Features the most comprehensive coverage of the literature on RSD and its related aspects＜/p＞ ＜p＞Describes qualitative and quantitative differences between natural endorphins and systemic narcotics＜/p＞ ＜p＞Examines the role of ACTH in the management of chronic pain＜/p＞ ＜p＞Clarifies the mechanism of development of RSD through an extensive collection of drawings and anatomical pictures＜/p＞ ＜p＞Explains why sympathectomy fails, but nerve block and physiotherapy is successful in the treatment of RSD＜/p＞画面が切り替わりますので、しばらくお待ち下さい。
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＜p＞This handbook offers a theoretical foundation for the adaptation of Parent-Child Interaction Therapy (PCIT) for children with autism spectrum disorder (ASD) and their families. The volume examines current treatments for children with ASD and provides a rationale for why PCIT is considered a strong option to address many of the concerns found within this population of children and families. It presents an overview of PCIT theory, the goals of PCIT, the unique aspects of the treatment, and the exceptional outcomes. The handbook demonstrates the versatility of PCIT in conjunction with standard science-based therapies in addressing specific behavioral problems in this young population. Chapters provide a theoretical basis for PCIT, the empirical evidence for its efficacy, clinical considerations, and training issues. Chapters also offer a selection of case studies that help illustrate how PCIT has been successful in treating children with autism. The handbook concludes by identifying the gaps that need to be addressed by future research.＜/p＞ ＜p＞Topics featured in the ＜em＞Handbook＜/em＞ include:＜/p＞ ＜ul＞ ＜li＞ ＜p＞A clinical description of Parent-Child Interaction Therapy.＜/p＞ ＜/li＞ ＜li＞ ＜p＞The effects of medication for individuals with ASD.＜/p＞ ＜/li＞ ＜li＞ ＜p＞The importance of parent-child interactions in social communication and development.＜/p＞ ＜/li＞ ＜li＞ ＜p＞Teaching complex social behavior to children with ASD.＜/p＞ ＜/li＞ ＜li＞ ＜p＞Internet-delivered PCIT (I-PCIT) for children with autism.＜/p＞ ＜/li＞ ＜li＞ ＜p＞Child-Directed Interaction treatments for children with ASD.＜/p＞ ＜/li＞ ＜li＞ ＜p＞Parent-Directed Interaction treatments for children on the autism spectrum.＜/p＞ ＜/li＞ ＜/ul＞ ＜p＞The ＜em＞Handbook of Parent-Child Interaction Therapy for Children on the Autism Spectrum＜/em＞ is a must-have resource for researchers, professors, clinicians/practitioners/therapists, and graduate students across many interrelated disciplines, including child and school psychology, behavioral therapy, social work, child and adolescent psychiatry, pediatrics, and family studies as well as occupational therapy, physical therapy, behavior analysis, and speech therapy.＜/p＞画面が切り替わりますので、しばらくお待ち下さい。
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＜p＞This comprehensive title presents an accessible overview of the state of the art in General Surgery and Surgical Specialties, an applied medical field that combines science, technical know how and manual dexterity. Written by leading experts from universities in various regions of Brazil and international partners, it discusses all surgical fields clearly and concisely, providing readers with fundamental insights that they can apply in their daily practice.＜/p＞ ＜p＞Taking into consideration different local environments and resources, the book presents feasible diagnostic and treatment options, allowing clinicians to provide state of the art care in their given circumstances. As such, it offers a vital contribution to health care in developed countries as well as in remote areas.＜/p＞ ＜p＞The book includes 101 chapters in a practical format. Intended for general physicians, medical students and residents in general surgery, as well as fellows in various surgical specialties, it is the first book combining complex theoretical and practical knowledge in a way that allows surgeons and non-surgeons alike to understand and quickly access information for their treatment decisions.＜/p＞画面が切り替わりますので、しばらくお待ち下さい。
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＜p＞This collection re-imagines the field of criminology with insights gleaned from feminist theory. Works included here illustrate that gender is a key organizing principle of social life. This means that men and women have gender, that patriarchy as well as gender must be theorized, and that other systems of oppression such as race and class must also be studied to fully understand the crime problem and the criminal justice system. Finally, the articles collected here exemplify the feminist concern for thinking consciously about how and why we do our research with the crucial goal of producing knowledge that will promote social justice.＜/p＞画面が切り替わりますので、しばらくお待ち下さい。
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＜p＞This catalogue of the Shakespeare First Folio (1623) is the result of two decades of research during which 232 surviving copies of this immeasurably important book were located a remarkable 72 more than were recorded in the previous census over a century ago and examined in situ, creating an essential reference work.＜/p＞画面が切り替わりますので、しばらくお待ち下さい。
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＜p＞The only book series to summarize the latest progress on organic reaction mechanisms, ＜em＞Organic Reaction Mechanisms, 2011＜/em＞ surveys the development in understanding of the main classes of organic reaction mechanisms reported in the primary scientific literature in 2011. The 47th annual volume in this highly successful series highlights mechanisms of stereo-specific reactions. Reviews are compiled by a team of experienced editors and authors, allowing advanced undergraduates, graduate students, postdocs, and chemists to rely on the volume's continuing quality of selection and presentation.＜/p＞画面が切り替わりますので、しばらくお待ち下さい。
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＜p＞［この電子書籍は固定型レイアウトです。
リフロー型と異なりビューア機能が制限されます］固定型レイアウトはページを画像化した構造であるため、ページの拡大縮小を除く機能は利用できません。
また、モノクロ表示の端末ではカラーページ部分で一部見づらい場合があります。
＜/p＞ ＜p＞2015年度の電子書籍市場規模は1,584億円と推計され、2014年度の1,266億円から318億円増加。
電子雑誌市場規模は242億円と推計され、電子書籍と電子雑誌を合わせた電子出版市場は1,826億円となり、市場は順調に拡大している。
今年度から急成長しているマンガアプリ関連の広告市場に関する市場規模を算出している。
＜br /＞ 電子書籍市場は引き続き電子コミックが好調で市場を牽引している。
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また、複数の無料マンガアプリが1000万ダウンロードを超えるなど、新たなビジネスモデルも急速に成長し始めている。
＜br /＞ 本調査報告書は、このような電子書籍市場について、市場規模分析や各関連プレイヤーの動向、国内及びアメリカの電子書籍分野で理解すべき最新動向、ユーザーの電子書籍の利用動向など多角的に分析している。
今年度のユーザー調査では、従来のPCでのインターネットユーザへの調査およびスマートフォンユーザーに特化した調査のふたつを実施している。
この一冊で電子書籍ビジネスを網羅的に理解できる調査報告書である。
＜br /＞ なお本調査報告書は、電子書籍販売ストア、取次、出版社への取材、ユーザーへのアンケート調査等をまとめたものである。
本調査報告書は電子書籍ビジネス黎明期の2003年に第1号目を発行し、今年で14年目を迎える。
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＜p＞Financial crime affects virtually all areas of public policy and is increasingly transnational. The essays in this volume address both the theoretical and policy issues arising from financial crime and feature a wide variety of case studies, and cover topics such as state revenue collection, criminal enterprises, money laundering, the use of new technologies and methods in financial crime, corruption, terrorism, proliferation of WMD, sanctions, third-world debt, procurement, telecommunications, cyberspace, the defense industry and intellectual property. Taken together, these essays form a must-read collection for scholars and students in law, finance and criminology.＜/p＞画面が切り替わりますので、しばらくお待ち下さい。
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＜p＞Optical science, engineering, and technology have grown rapidly in the last decade so that today optical engineering has emerged as an important discipline in its own right. This series is devoted to discussing topics in optical engineering at a level that will be useful to those working in the field or attempting to design systems that are based on optical techniques or that have significant optical subsystems.＜/p＞画面が切り替わりますので、しばらくお待ち下さい。
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